This book presents an overview of potential natural geroprotectors, including substances such as urolithin A, alpha-ketoglutarate, trigonelline (TRG), taurine, melatonin, berberine, spermidine, lycopene, pyrroloquinoline quinone (PQQ), ergothioneine, dehydroepiandrosterone (DHEA), fisetin, glucosamine, coenzyme Q10, lutein/zeaxanthin, vitamin K, carnosine, magnesium, lithium, N-acetylcysteine (NAC), glycine, serine, resveratrol, and curcumin, among others. For each compound, research data is provided demonstrating their potential geroprotective properties, mechanisms of action, and effects on the lifespan of model organisms.